Researchers are now exploring the potential of peripheral neuropathy stem cells to alleviate the symptoms of degenerative diseases like diabetes. These cells may have an anti-inflammatory effect on diabetic nerves, a feature of neuropathy that is characteristic of diabetes. They may also help in modulating the immune system, improving the quality of life for people with mesenchymal peripheral neuropathy stem cell. To understand how stem cells can be useful in treating neuropathy, researchers must investigate the mechanisms that trigger cell growth, study the effect in vivo, and involve patients with the condition.
Despite the promising benefits of stem cells, idiopathic peripheral neuropathy is difficult to treat with traditional medical techniques. Treatments such as pain medications, antidepressants, and opioid pain medications can help alleviate symptoms but are not a cure. In severe cases, patients may need a combination of drugs. These treatments are not only costly, but they may also have side effects. Stem cell therapy is a promising treatment for this disorder, as it can help regenerate nerve cells and heal damaged nerves.
While stem cell treatments are effective, patients must remember that they may not qualify for the procedure. People with severe underlying conditions like autoimmune diseases and inflammatory disorders may not be a good candidate. Because current treatments merely mask the symptoms, stem cell therapy offers an alternative to invasive and painful surgeries. Besides addressing the underlying causes of neuropathy, stem cell treatments may even help prevent the onset of the disease in the first place.
Found that in mice with CCI :
Peripheral neuropathy stem cell treatments have demonstrated improved quality of life and reduced the severity of symptoms. The EDSS and MSFC scores of participants improved from 1.4 to 4.5 and -0.01 to 0.64, respectively. In addition, the rate of progression and relapse-free survival was high. Finally, total quality of life scores improved from 46 to 49 at two and four years, respectively. These results are promising, and may prove to be the best treatment for peripheral neuropathy.
In addition to this, researchers have found that in mice with CCI, intrathecal injection of siRNA-treated BMSCs reduced the number of stem cells in the injured DRG and diminished the inhibitory effect on NP mechanical hypersensitivity. This method of intravenous delivery of MSCs has also been found to trap the cells in lungs. In addition, experimental evidence has also shown that MSCs are capable of homeostasis, and the transplantation of them in rats with CCI has increased the number of neuronal tissues.
Unfortunately, not all clinics offering peripheral neuropathy stem cell treatments are actually selling stem cells. The stem cells sold to these clinics are not FDA-approved and are often derived from umbilical cords that have not undergone FDA approval. The product is misregistered, and the FDA has warned companies that are selling these products as stem cells to consumers. It is important to be wary of scams. And remember that the best treatment for peripheral neuropathy is to get the proper diagnosis before making any decisions.
Treatments for peripheral neuropathy:
Until now, there are no effective treatments for peripheral neuropathy. Prescription drugs and surgery have failed to provide any real benefit for the condition. In fact, most physicians do not want to inform patients about the treatment options available. Instead, they will tell you that there are no known cures for peripheral neuropathy, and then prescribe powerful painkillers. This approach may be the future of neuropathy. The potential benefits are too great to ignore.
While clinical trials have indicated the benefits of stem cells for neuropathy, more research is needed to determine the right dose and delivery method. There are many fraudulent centers out there that prey on vulnerable patients. In addition, the research has been limited to only a few patients, and there is still no FDA approval for this treatment. However, this promising trend is attracting the attention of researchers across the world. In the meantime, patients should be vigilant when choosing a center to receive stem cell therapy.
The treatment for peripheral neuropathy uses tissue-engineered nerve grafts made from stem cells. These nerve grafts contain bioscaffolds, seed cells, and neurotrophic factors. When implanted into a patient, stem cells can differentiate into Schwann-like cells and produce a neurotrophic environment that promotes nerve regeneration. These nerve grafts can repair up to 6 cm of peripheral nerve defect, which may seem like a miracle.